49ers vs Colts

Final · Week 16 · Mon Dec 22 · 8:15 PM ET · Lucas Oil Stadium

San Francisco 49ers49ers11-4

FinalDec 22, 2025

Indianapolis ColtsColts8-7

TVESPNABC

Closing line

US sportsbook at kickoff

Moneyline

SF−225

IND+185

Spread

SF −4.5−105

IND +4.5−115

Total O/U

Over 46.5−102

Under 46.5−118

Spread: 49ers −4.5 covered.
Total O/U: over 46.5 (75 points).

Recap

The San Francisco 49ers routed the Indianapolis Colts 48-27 at Lucas Oil Stadium in Indianapolis on Dec 22, 2025, a 21-point win to move to 11-4.

The game was played before 66,265.

Score by quarter

San Francisco 49ers and Indianapolis Colts, score by quarter
Team	1	2	3	4	T
SF	14	10	10	14	48
IND	7	10	3	7	27

Scoring plays

First Quarter

INDTouchdown · 10:31Alec Pierce 20 Yd pass from Philip Rivers (Blake Grupe Kick)0-7
SFTouchdown · 7:14Demarcus Robinson 22 Yd pass from Brock Purdy (Eddy Pineiro Kick)7-7
SFTouchdown · 4:33Christian McCaffrey 2 Yd pass from Brock Purdy (Eddy Pineiro Kick)14-7

Second Quarter

INDTouchdown · 14:15Alec Pierce 16 Yd pass from Philip Rivers (Blake Grupe Kick)14-14
SFTouchdown · 9:36George Kittle 11 Yd pass from Brock Purdy (Eddy Pineiro Kick)21-14
SFField Goal · 1:51Eddy Pineiro 25 Yd Field Goal24-14
INDField Goal · 0:17Blake Grupe 39 Yd Field Goal24-17

Third Quarter

SFTouchdown · 10:58Jauan Jennings 3 Yd pass from Brock Purdy (Eddy Pineiro Kick)31-17
INDField Goal · 8:16Blake Grupe 51 Yd Field Goal31-20
SFField Goal · 4:02Eddy Pineiro 38 Yd Field Goal34-20

Fourth Quarter

INDTouchdown · 12:41Jonathan Taylor 1 Yd Rush (Blake Grupe Kick)34-27
SFTouchdown · 7:37Christian McCaffrey 9 Yd pass from Brock Purdy (Eddy Pineiro Kick)41-27
SFTouchdown · 3:26Dee Winters 74 Yd Interception Return (Eddy Pineiro Kick)48-27

Team stats

SFIND

1st Downs: 28; 19
Total Yards: 440; 312
Passing: 295; 254
Rushing: 145; 58
3rd down efficiency: 7-11; 5-10
Turnovers: 1; 2
Possession: 33:05; 26:55

Top performers

San Francisco 49ersIndianapolis Colts

Passing

Brock Purdy25/34, 295 YDS, 5 TD, 1 INT

Philip Rivers23/35, 277 YDS, 2 TD, 1 INT

Rushing

Christian McCaffrey21 CAR, 117 YDS

Jonathan Taylor16 CAR, 46 YDS, 1 TD

Receiving

George Kittle7 REC, 115 YDS, 1 TD

Alec Pierce4 REC, 86 YDS, 2 TD

Sacks

Alfred Collins1

Laiatu Latu1

Tackles

Tatum Bethune9

Cam Bynum7

Player stats

49ers · Passing

Player	C/ATT	YDS	AVG	TD	INT	SACKS	QBR	RTG
Brock Purdy	25/34	295	8.7	5	1	1-0	88.6	126.8

49ers · Rushing

Player	CAR	YDS	AVG	LONG
Christian McCaffrey	21	117	5.6	24
Brian Robinson Jr.	5	20	4.0	11
Brock Purdy	2	11	5.5	9
Mac Jones	3	-3	-1.0	-1

49ers · Receiving

Player	REC	YDS	AVG	TD	LONG	TGTS
George Kittle	7	115	16.4	1	26	8
Jauan Jennings	5	71	14.2	1	21	6
Christian McCaffrey	6	29	4.8	2	10	8
Kendrick Bourne	3	27	9.0	0	14	5
Demarcus Robinson	2	23	11.5	1	22	2
Skyy Moore	1	23	23.0	0	23	1
Jake Tonges	1	7	7.0	0	7	2
Brian Robinson Jr.	0	0	0.0	0	0	1

49ers · Fumbles

Player	FUM	REC
Brock Purdy	1	0
Luke Farrell	0	1
Jake Tonges	0	1

49ers · Defense

Player	TOT	SOLO	TFL	PD	QB HTS	TD
Ji'Ayir Brown	9	5	1	0	0	0
Tatum Bethune	9	4	0	1	0	0
Malik Mustapha	8	3	0	0	1	0
Darrell Luter Jr.	6	5	0	1	0	0
Upton Stout	6	3	0	2	0	0
Deommodore Lenoir	3	2	0	0	0	0
Keion White	3	1	0	0	1	0
Dee Winters	3	1	0	2	0	1

49ers · Interceptions

Player	INT	YDS	TD
Dee Winters	1	74	1

49ers · Kick returns

Player	NO	YDS	AVG	LONG	TD
Skyy Moore	4	112	28.0	36	0
Brian Robinson Jr.	2	55	27.5	31	0

49ers · Punt returns

Player	NO	YDS	AVG	LONG	TD
Skyy Moore	1	8	8.0	8	0

49ers · Kicking

Player	FG	PCT	LONG	XP	PTS
Eddy Pineiro	2/3	66.7	38	6/6	12

Colts · Passing

Player	C/ATT	YDS	AVG	TD	INT	SACKS	QBR	RTG
Philip Rivers	23/35	277	7.9	2	1	2-23	52.2	97.0
Riley Leonard	0/1	0	0.0	0	0	0-0	2.2	39.6

Colts · Rushing

Player	CAR	YDS	AVG	TD	LONG
Jonathan Taylor	16	46	2.9	1	7
Tyler Goodson	3	9	3.0	0	6
Josh Downs	1	3	3.0	0	3

Colts · Receiving

Player	REC	YDS	AVG	TD	LONG	TGTS
Alec Pierce	4	86	21.5	2	33	4
Josh Downs	5	65	13.0	0	18	9
Jonathan Taylor	3	33	11.0	0	19	3
Michael Pittman Jr.	4	32	8.0	0	14	5
Tyler Warren	3	30	10.0	0	19	9
Mo Alie-Cox	2	16	8.0	0	8	2
Drew Ogletree	1	11	11.0	0	11	2
Ameer Abdullah	1	4	4.0	0	4	1
Coleman Owen	0	0	0.0	0	0	1

Colts · Fumbles

Player	FUM	LOST	REC
Ameer Abdullah	1	1	0
Philip Rivers	1	0	0
Danny Pinter	0	0	1

Colts · Defense

Player	TOT	SOLO	SACKS	TFL	PD	QB HTS
Cam Bynum	7	5	0	0	1	0
Germaine Pratt	6	4	0	0	1	0
Nick Cross	6	3	0	0	0	0
DeForest Buckner	5	4	0	0	0	0
Cameron Mitchell	4	4	0	1	0	0
Samson Ebukam	4	3	0	0	0	0
Zaire Franklin	4	2	0	0	1	0
Laiatu Latu	3	3	1	1	0	1

Colts · Interceptions

Player	INT	YDS	TD
Cam Bynum	1	8	0

Colts · Kick returns

Player	NO	YDS	AVG	LONG
Coleman Owen	3	89	29.7	33
Tyler Goodson	2	60	30.0	31
Ameer Abdullah	1	17	17.0	17

Colts · Kicking

Player	FG	PCT	LONG	XP	PTS
Blake Grupe	2/2	100.0	51	3/3	9

Colts · Punting

Player	NO	YDS	AVG	TB	In 20	LONG
Rigoberto Sanchez	2	101	50.5	0	1	54

Game info

VenueLucas Oil Stadium, Indianapolis, IN

Attendance66,265

OfficialsUmpire: Barry Anderson · Side Judge: Keith Washington · Referee: Ronald Torbert · Field Judge: Ryan Dickson

TVESPN · nationalABC · national

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Game details updated Oct 13, 5:54 PM ET. How game pages are made