49ers vs Cardinals

Final · Week 11 · Sun Nov 16 · 4:05 PM ET · State Farm Stadium

San Francisco 49ers49ers7-4

FinalNov 16, 2025

Arizona CardinalsCardinals3-7

TVFox

Closing line

US sportsbook at kickoff

Moneyline

SF−215

ARI+180

Spread

SF −3.5−122

ARI +3.5+103

Total O/U

Over 48.5−115

Under 48.5−105

Spread: 49ers −3.5 covered.
Total O/U: over 48.5 (63 points).

Recap

The San Francisco 49ers beat the Arizona Cardinals 41-22 at State Farm Stadium in Glendale on Nov 16, 2025 to move to 7-4.

The 49ers won the turnover battle 3-0. The 49ers won despite being outgained 488-281 in total yards.

Score by quarter

San Francisco 49ers and Arizona Cardinals, score by quarter
Team	1	2	3	4	T
SF	13	12	10	6	41
ARI	7	3	0	12	22

Scoring plays

First Quarter

SFTouchdown · 14:44Christian McCaffrey 1 Yd Rush (Eddy Pineiro Kick)7-0
SFTouchdown · 9:51George Kittle 30 Yd pass from Brock Purdy (Eddy Pineiro PAT blocked)13-0
ARITouchdown · 4:58Bam Knight 6 Yd Rush (Chad Ryland Kick)13-7

Second Quarter

SFTouchdown · 13:39Christian McCaffrey 9 Yd pass from Brock Purdy (Eddy Pineiro PAT Failed)19-7
ARIField Goal · 6:29Chad Ryland 26 Yd Field Goal19-10
SFField Goal · 1:01Eddy Pineiro 48 Yd Field Goal22-10
SFField Goal · 0:00Eddy Pineiro 47 Yd Field Goal25-10

Third Quarter

SFField Goal · 7:27Eddy Pineiro 47 Yd Field Goal28-10
SFTouchdown · 2:32George Kittle 4 Yd pass from Brock Purdy (Eddy Pineiro Kick)35-10

Fourth Quarter

ARITouchdown · 8:28Trey McBride 10 Yd pass from Jacoby Brissett (Two-Point Run Conversion Failed)35-16
SFTouchdown · 4:44Christian McCaffrey 4 Yd Rush (Two-Point Pass Conversion Failed)41-16
ARITouchdown · 2:43Greg Dortch 17 Yd pass from Jacoby Brissett (Two-Point Pass Conversion Failed)41-22

Team stats

SFARI

1st Downs: 24; 24
Total Yards: 281; 488
Passing: 186; 452
Rushing: 95; 36
3rd down efficiency: 3-9; 6-14
Turnovers: 0; 3
Possession: 25:45; 34:15

Top performers

San Francisco 49ersArizona Cardinals

Passing

Brock Purdy19/26, 200 YDS, 3 TD

Jacoby Brissett47/57, 452 YDS, 2 TD, 2 INT

Rushing

Christian McCaffrey13 CAR, 81 YDS, 2 TD

Bam Knight5 CAR, 24 YDS, 1 TD

Receiving

George Kittle6 REC, 67 YDS, 2 TD

Michael Wilson15 REC, 185 YDS

Sacks

–

Josh Sweat1

Tackles

Curtis Robinson12

Cody Simon12

Player stats

49ers · Passing

Player	C/ATT	YDS	AVG	TD	INT	SACKS	QBR	RTG
Brock Purdy	19/26	200	7.7	3	0	1-14	71.2	133.5

49ers · Rushing

Player	CAR	YDS	AVG	TD	LONG
Christian McCaffrey	13	81	6.2	2	20
Brian Robinson Jr.	8	24	3.0	0	7
Mac Jones	3	-3	-1.0	0	-1
Brock Purdy	1	-7	-7.0	0	-7

49ers · Receiving

Player	REC	YDS	AVG	TD	LONG	TGTS
George Kittle	6	67	11.2	2	30	6
Jauan Jennings	4	54	13.5	0	25	6
Christian McCaffrey	5	40	8.0	1	15	6
Kyle Juszczyk	2	26	13.0	0	21	2
Demarcus Robinson	1	13	13.0	0	13	2
Brian Robinson Jr.	0	0	0.0	0	0	1
Ricky Pearsall	1	0	0.0	0	0	2

49ers · Fumbles

Player	FUM	LOST	REC
Keion White	0	0	1

49ers · Defense

Player	TOT	SOLO	TFL	PD
Curtis Robinson	12	5	0	0
Dee Winters	10	5	1	0
Nick Martin	7	5	0	0
Deommodore Lenoir	7	4	0	2
Ji'Ayir Brown	7	3	0	0
Upton Stout	7	2	0	0
Renardo Green	6	4	0	0
Jason Pinnock	5	3	1	0

49ers · Interceptions

Player	INT	YDS	TD
Deommodore Lenoir	1	64	0
Malik Mustapha	1	0	0

49ers · Kick returns

Player	NO	YDS	AVG	LONG	TD
Skyy Moore	1	98	98.0	98	0
Brian Robinson Jr.	1	42	42.0	42	0

49ers · Punt returns

Player	NO	YDS	AVG	LONG	TD
Skyy Moore	1	9	9.0	9	0

49ers · Kicking

Player	FG	PCT	LONG	XP	PTS
Eddy Pineiro	3/3	100.0	48	2/4	11

49ers · Punting

Player	NO	YDS	AVG	TB	In 20	LONG
Thomas Morstead	3	139	46.3	0	1	55

Cardinals · Passing

Player	C/ATT	YDS	AVG	TD	INT	SACKS	QBR	RTG
Jacoby Brissett	47/57	452	7.9	2	2	0-0	25.9	96.8

Cardinals · Rushing

Player	CAR	YDS	AVG	TD	LONG
Bam Knight	5	24	4.8	1	7
Emari Demercado	5	8	1.6	0	5
Michael Carter	2	6	3.0	0	3
Jacoby Brissett	2	-2	-1.0	0	2

Cardinals · Receiving

Player	REC	YDS	AVG	TD	LONG	TGTS
Michael Wilson	15	185	12.3	0	34	18
Trey McBride	10	115	11.5	1	28	11
Greg Dortch	6	66	11.0	1	17	6
Michael Carter	5	22	4.4	0	7	7
Bam Knight	4	21	5.3	0	12	4
Xavier Weaver	2	15	7.5	0	9	3
Emari Demercado	2	12	6.0	0	9	3
Elijah Higgins	2	11	5.5	0	6	3
Andre Baccellia	1	5	5.0	0	5	1

Cardinals · Fumbles

Player	FUM	LOST	REC
Elijah Higgins	1	1	0

Cardinals · Defense

Player	TOT	SOLO	PD
Cody Simon	12	4	0
Budda Baker	8	3	0
Jalen Thompson	5	2	1
Darius Robinson	5	1	0
Max Melton	4	2	1
Akeem Davis-Gaither	4	1	0
PJ Mustipher	3	2	0
Garrett Williams	3	1	1

Cardinals · Kick returns

Player	NO	YDS	AVG	LONG
Greg Dortch	3	79	26.3	31
Andre Baccellia	3	74	24.7	27
Michael Carter	1	27	27.0	27

Cardinals · Punt returns

Player	NO	YDS	AVG	LONG	TD
Greg Dortch	2	51	25.5	40	0

Cardinals · Kicking

Player	FG	PCT	LONG	XP	PTS
Chad Ryland	1/2	50.0	26	1/1	4

Cardinals · Punting

Player	NO	YDS	AVG	TB	In 20	LONG
Pat O'Donnell	3	122	40.7	0	0	46

Game info

VenueState Farm Stadium, Glendale, AZ

Attendance65,032

OfficialsReferee: Carl Cheffers · Back Judge: Martin Hankins · Side Judge: Eugene Hall · Field Judge: Nathan Jones

TVFox · national

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Game details updated Oct 13, 5:54 PM ET. How game pages are made