MLB Scores · MLB Odds

Astros vs Cubs

Final · Fri May 22 · 2:20 PM ET · Wrigley Field

Houston AstrosAstros21-31
4
FinalMay 22, 2026
Chicago CubsCubs29-22
2
StreamApple TV

Closing line

US sportsbook at first pitch
Moneyline
HOU+123
CHC−148
Run line
HOU +1.5−187
CHC −1.5+153
Total O/U
Over 7+101
Under 7−121
  • Run line: Astros +1.5 covered.
  • Total O/U: under 7 (6 runs).

Recap

The Houston Astros beat the Chicago Cubs 4-2 at Wrigley Field in Chicago on May 22, 2026 to move to 21-31.

The game was played before 37,332.

Score by inning

Houston Astros and Chicago Cubs, score by inning
Team123456789R
HOU0012100004
CHC0000020002

W: Arrighetti (6-1) · L: Taillon (2-4) · S: King (0-1)

Scoring plays

Top 3

  1. HOUHome runVázquez homered to left center (371 feet).1-0

Top 4

  1. HOUFielder's choiceCole grounded into fielder's choice to shortstop, Walker scored, Smith out at second, Shewmake to third.2-0
  2. HOUSingleVázquez singled to right, Shewmake scored, Cole to third.3-0

Top 5

  1. HOUSingleMatthews singled to center, Paredes scored, Meyers to second.4-0

Bottom 6

  1. CHCHome runCrow-Armstrong homered to right (406 feet), Amaya scored.4-2

Team stats

HOUCHC
Hits
9
4
Home Runs
1
1
Runs Batted In
4
2
Walks
4
5
Strikeouts
10
6
Runners Left On Base
21
22
Errors
2
0

Player stats

Astros · Batting

PlayerH-ABABRHRBIHRBBK#PAVGOBPSLG
Jeremy Pena SS1-5501000119.254.297.322
Isaac Paredes 3B1-4411001020.244.335.375
Yordan Alvarez DH1-3301002128.303.416.601
Christian Walker 1B1-5511000320.254.327.481
Jake Meyers CF1-440100019.229.296.333
Braden Shewmake 2B0-111000107.286.298.482
Brice Matthews 2B1-220110017.207.260.355
Nick Allen 2B0-000000000.235.297.265
Cam Smith RF1-4401000118.207.298.317
Zach Cole LF0-4400100119.170.188.383
Christian Vazquez C2-4412210120.258.324.430

Astros · Pitching

PlayerIPHRERBBKHRPC-STERAPC
Spencer Arrighetti P5.020045089-531.3289
Steven Okert P0.12220016-54.226
Enyel De Los Santos P1.200001019-134.0519
Bryan Abreu P0.200010014-67.3114
Bryan King P1.100000017-122.8217

Cubs · Batting

PlayerH-ABABRHRBIHRBBK#PAVGOBPSLG
Nico Hoerner 2B0-4400001117.259.345.383
Michael Busch 1B0-3300001024.229.361.369
Alex Bregman 3B1-3301001019.250.338.350
Ian Happ LF1-5501000218.214.350.429
Seiya Suzuki RF0-4400000014.254.354.435
Michael Conforto DH0-220000018.311.419.590
Miguel Amaya DH1-111100002.247.360.397
Moises Ballesteros DH0-110000001.241.298.446
Carson Kelly C0-3300000115.289.377.388
Pete Crow-Armstrong CF1-2211212016.228.311.375
Dansby Swanson SS0-4400000111.187.289.349

Cubs · Pitching

PlayerIPHRERBBKHRPC-STERAPC
Jameson Taillon P4.284415190-595.2090
Hoby Milner P0.11000008-51.938
Ethan Roberts P2.000012032-180.7932
Jacob Webb P1.000002015-102.9115
Phil Maton P1.000021022-118.4022

Scores, stats and closing line: ESPN. Prediction-market prices: Kalshi and Polymarket. Betting splits: a consensus across several sportsbooks. Odds change constantly: confirm the price at the book. 21+. Gambling problem? Call 1-800-GAMBLER.

Game details updated Oct 13, 4:51 PM ET. How game pages are made